Reactive Flow Modeling (IMFT)
The team 'Reactive flow modeling' has an established interdisciplinary experience in the domain of image/model coupling from cell to organ-scale such as flow modeling and its relationship with metabolic issues, from cell to entire-organ scale, either inside in-silico experiments or ex-vivo/in-vivo tissues. The team is concern by gathering together relevant 3D images (e.g optical, acoustical) related to the intimate tissue physiology with meso-scale modeling in order to reach a better understanding of integrated couplings, in various organs. The goal inside RESTORE is to develop this expertise to help understanding tissue heterogeneity, identify relevant couplings, so as to help understanding the tissue remodeling and aging. Furthermore, the expression of flux modeling with metabolomic analysis is a topic of interest for future research inside RESTORE, based upon the idea that cells response are coupled to their local (possibly complex) environment.
The team uses and develop dedicated image-processing workflow to address practical issues related to (possibly huge) 3D image post-processing either with the aim of reaching state of the art methods.
F. Plouraboué (DR CNRS ), G. Debenest (PR INPT ), P. Keemmel (post-doc ), J. Duchamp (PhD)