Présentation des activités scientifiques du laboratoire Interactions moléculaires et réactivité chimique et photochimique – IMRCP Le laboratoire des IMRCP est une unité étudiant l’organisation de molécules (tensioactifs, lipides…), de nanoparticules (organiques ou inorganique) et de polymères (naturels ou non), en solution mais aussi en masse. Cette organisation est responsable de multiples propriétés et applications tant […]

Lifelong orchestration of animal physiology by the circadian clock To improve their adaptation to the changing environment presents on Earth, organisms from bacteria to mammals have evolved a timing system that anticipates these changes. This endogenous timing system, called the circadian clock, orchestrates most aspects of physiology and behavior. The mammalian circadian clock is hierarchically […]

Revisiting chemotherapy: drug persisters arise from metabolically and transcriptionally distinct cell populations in leukemia Relapses caused by drug resistance is the major barrier for effective treatment of most solid tumors and hematological malignancies. In acute myeloid leukemia (AML), we showed that mitochondrial adaptation is a critical determinant of resistance to cytarabine (AraC). We proved that […]