Aging : the promoting role of telomeres ? Éric Gilson is PU-PH at Université Côte d’Azur and Nice University Hospital. He heads the “Telomere, Senescence and Cancer” team at IRCAN (Institute for Research on Cancer and Aging, Nice), a laboratory unit devoted to aging which he founded in 2012. His research focuses on deciphering how telomeres contribute […]
Supercontinuum-multiplexed CARS hyperspectral imaging for label-free discrimination of muscle proteins Claire Lefort will present recent advances from the MyoSense project, focusing on multiplex CARS (Coherent Anti-Stokes Raman Scattering) imaging for probing muscle tissues. By leveraging supercontinuum excitation and hyperspectral analysis, this approach simultaneously captures resonant and non-resonant signals. She will show that the so-called “silent […]
Functional heterogeneity of tumor-associated macrophages in pleural mesothelioma reveals tumoricidal immune activity Malik Hamaidia is a postdoctoral researcher at the GIGA Cancer Institute (University of Liège) studying macrophage biology and tumor–immune interactions. His work focuses on the functional heterogeneity of tumor-associated macrophages in pleural mesothelioma and their capacity to exert tumoricidal activity within the tumor […]
Genesys: a FAIR and collaborative cloud platform for multi-omics research We will introduce Genesys, a collaborative cloud platform designed to centralize, explore, and exploit multi-omics data within a fully FAIR and reproducible framework. Genesys structures analyses, documents every step, facilitates project management, and enables interactive result exploration as well as figure panel organization. This approach […]
Trajectoire de vieillissement chez le chien : exploration biologique et évaluation d’une solution nutritionnelle Le chien, partageant notre environnement mais vieillissant plus rapidement, constitue un modèle translationnel pertinent du vieillissement humain. À l’aide d’un phénotype de fragilité déjà décrit chez le chien, nous avons caractérisé la trajectoire du vieillissement canin dans une approche intégrative (clinique, […]
Approches interdisciplinaires basées sur les -omiques et la science des matériaux pour l’étude des interactions cellules-matériaux en médecine régénérative Après avoir obtenu son doctorat en sciences des biomatériaux à l’Université de Toulouse en 2009, H. Autefage a rejoint le groupe du Prof. Stevens à Imperial College London, au Royaume-Uni, en tant que post-doctorante. Depuis 2016, […]
Are Dementias a Consequence of Accelerated Aging? Élise Marsan est neuroscientifique, spécialisée en neurobiologie cellulaire et moléculaire. Elle a obtenu son doctorat auprès des Universités de la Sorbonne pour ses travaux menés à l’Institut du Cerveau à Paris, portant sur l’implication de la voie mTOR dans les épilepsies familiales et les malformations cérébrales. Son expertise […]
Interorgan communication: a drosophila perspective Norbert Perrimon wants to understand how cells, tissues, and organs communicate during development. Working in Drosophila, Perrimon’s lab group uses techniques such as genome-wide RNAi and CRISPR screening and large-scale mass spectrometry to identify components of signaling networks and points of intersection, or “cross-talk nodes,” between signaling pathways that produce […]
Adipose Tissue Remodeling and Its Role in Energy Metabolism White adipose tissue (WAT) is a central organ of lipid and glucose metabolism that impacts systemic energy homeostasis. WAT actively senses nutritional changes and accordingly stores extra energy in the form of triglycerides or supplies nutrients to other organs. Also, WAT regulates whole-body energy metabolism by […]
Organoid human cancer immunity model in motion Dr Anne Rios will present a dynamic 3D imaging and integrated transcriptomics platform; BEHAV3D5, that has been developed to exploit immune-organoid co-cultures for understanding and improving the dynamic mode-of-action of engineered T cells in a patient personalized manner. Applied to various solid tumor types modeled with patient derived […]