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Amandine Girousse


About me
  • CNRS Researcher at RESTORE institute, Toulouse, France (since 2021)
  • Senior research associate / chargé de recherche at Stromalab, Toulouse, France (from 2016 to 2020)
  • Post doctoral fellow at Stromalab, Toulouse, France from 2015 to 2016
  • Post doctoral fellow in Savage’s laboratory, Institute of Metabolic Science, Cambridge University, United Kingdom from 2011 to 2015
  • Doctor in Veterinary Medicine, Toulouse, France, 2009
  • PhD student in Langin’s laboratory, Institute of Cardiovascular and Metabolic Diseases, Toulouse, France from 2006 to 2010
  • Master “Pharmacological innovations”, University Toulouse III Paul Sabatier, Toulouse, France (from 2005 to 2006)
  • Veterinary school student, Toulouse, France from 2002 to 2006
  • Bachelor degree in Physiology/Biochemistry (2002) at the Montpellier II University, France
Research interests

I’m a researcher originating from veterinay medicine. For 10 years my scope of research was the integrated physiology of adipose tissue, from obesity to lipodystrophy and their associated metabolic disorders. Through the use of several transgenic mouse models and adipocytes in vitro models I studied the consequences of the deregulation of energy balance and fatty acids fluxes. More recently I explored adipose tissue beyonds its metabolics properties, with a focus on the role endogenous adipose stromal cells mobilization in fat ectopic deposition and distant skeletal muscle regeneration.

Scientific affiliations
  • AFERO, French association for the study of obesity , France
  • AFM Téléthon, French association for the study of Myopathies, France
  • CREFRE Ethics committee, Toulouse, France
  • Fascia research society
Publications / Patents
  • A. Girousse, M. Gil-Ortega, V. Bourlier, C. Bergeaud, Q. Sastourne-Arrey, C. Moro, C. Barreau, C. Guissard, J. Vion, E. Arnaud, J.P. Pradere, N. Juin, L. Casteilla and C. Sengenès. The release of adipose stromal cells from subcutaneous adipose tissue regulates ectopic intramuscular adipocyte deposition Cell Reports 2019 Apr 9;27(2):323-333
  • Girousse A., Virtue S., Hart D., Vidal-Puig A., Murgatroyd P.R.,Sengenès C., Mouisel E., SavageD.B. Surplus fat increases fat oxidation and hyperinsulinaemia in lipodystrophic mice. Molecular Metabolism, 2018 Jul;13:24-29
  • Carrière A, Jeanson Y, Côté JA, Dromard C, Galinier A, Menzel S, Barreau C, Dupuis-Coronas S, Arnaud E, Girousse A, Cuminetti V, Paupert J, Cousin B, Sengenes C, Koch-Nolte F, Tchernof A, Casteilla L. Identification of the ectoenzyme CD38 as a marker of committed preadipocytes. Int J Obes (Lond). 2017 Oct;41(10):1539-1546
  • F. Payne*, K. Lim*, A. Girousse*, R.J. Brown, N. Kory, A. Robbins, Y. Xue, A. Sleigh, E.K. Cochran, C. Adams, A. Dev Borman, D. Russel-Jones, P. Gorden, R.K. Semple, V. Saudek, S. O’Rahilly, T.C. Walther, I. Barroso, D.B. Savage. Mutations disrupting the Kennedy Phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease. PNAS 2014; 111(24)