Etiopathology of gingival inflammation: towards a new paradigm based on virus – bacteria synergy Periodontitis is one of the most common human inflammatory condition. This disease is responsible for tooth mobility and tooth loss, and it is also a significant risk factor for dozens of seemingly unrelated systemic illnesses. A polymicrobial dysbiosis model was proposed […]

Lessons for disease learned from cellular ageing: a 3D genome perspective We wish to uncover the rules governing gene expression in response to developmental and extra-cellular cues. Genome architecture is thought to be a major determinant in this. What we strive to understand is how chromatin (re)folds to accommodate responses to such cues in 3D […]