eMotion is a facility (scientific head: Prof. JC Portais) that provide to the scientific community with the tools and expertise to measure metabolic fluxes, including both carbon (matter) and electrons (energy) fluxes, at the biological scales ranging from 2D/3D cultured cells to whole organisms. eMotion encompasses one experimental plateau and two analytical plateaus:
- The experimental plateau (Head Dr Yannick Jeanson) integrates all the experimental stages ranging from the experimental design to its implementation until the samples collection. It also contains appropriate labs to perform in vitro or in vivo isotopic tracing experiments.
- The FluxoVivo plateau (Head Dr Spiro Khoury) which is dedicated to measuring carbon fluxes using isotopic tracing approaches.
- The RedoxHome plateau (Head Dr Yannick Jeanson) which contains different analytical devices allowing to assess electron fluxes (respiration, redox states of coenzymes, redox potential).
The name eMotion contains the idea of dynamics, and the overall objective of the facility is to provide support to measure the actual dynamics of metabolism.
FluxoVivo
RedoxHome
Métabolisme, adipocytes, métabolomique, fluxomique, traçage isotopique in vitro/in vivo, culture cellulaire en hypoxie, activité mitochondriale
Yannick Jeanson
Métabolisme, adipocytes, métabolomique, fluxomique, traçage isotopique in vitro/in vivo, activité mitochondriale
Spiro Khoury
- provide advice in the development of experiments,
- train the users,
- assist users in the analysis and interpretation of their results,
- assist users in the implementation of research and development projects, in the form of collaboration.